Thrombophlebitis is defined as the formation of a blood clot, or thrombus, and the development of vein inflammation, or phlebitis - a complication of superficial venous insufficiency. This condition is often being confused with deep vein thrombosis (DVT), which is the development of a blood clot with no inflammation in the veins of the deep system, a disease independent from thrombophlebitis. Thrombophlebitis is usually accompanied by swelling, pain, tenderness and redness, as opposed to DVT (where redness is never a symptom). Often, the thrombosed superficial vein can be felt under the skin, as a tender cord. Thrombophlebitis, as opposed to DVT, does not cause pulmonary embolism (PE), or blood clots thrown into the lungs, and, therefore, does not require anticoagulation, or blood thinning.

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