Thrombolysis usually refers to a minimally invasive, or performed through a needle-stick, procedure of breaking down a blood clot formed within a vessel. Traditionally, thrombolysis implies the utilization of pharmacological agents called thrombolytics. There are direct and indirect methods of thrombolysis. The direct one is safer, more efficient, but technically more challenging. During direct thrombolysis, a catheter delivering thrombolytics is placed inside or near the blood clot of interest. With indirect thrombolysis, the agent is being infused through a remote from the target clot vein. This approach is easy to establish, but it is less efficient and can be complicated by bleeding from other parts of the body.
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